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Do not take Cordarone with any of the following medications:
- abarelix
- amoxapine
- apomorphine
- arsenic trioxide
- certain macrolide antibiotics
- certain quinolone antibiotics
- cisapride
- droperidol
- haloperidol
- hawthorn
- levomethadyl
- maprotiline
- medicines for malaria like chloroquine and halofantrine
- medicines for mental depression such as tricyclic antidepressants
- medicines to control heart rhythm like disopyramide, dofetilide, ibutilide, propafenone, and sotalol
- methadone
- mibefradil
- pentamidine
- phenothiazines like chlorpromazine, mesoridazine, and thioridazine
- pimozide
- probucol
- ranolazine
- sertindole
- vardenafil
- red yeast rice
- ziprasidone
Cordarone may also interact with the following medications:
- beta blockers
- calcium channel blockers
- cholestyramine
- cimetidine
- clopidogrel
- cyclosporine
- dextromethorphan
- digoxin
- diuretics
- fentanyl
- flecainide
- fluindione
- general anesthetics
- grapefruit juice
- lidocaine
- loratadine
- medicines for fungal infections like ketoconazole, fluconazole, and itraconazole
- medicines for HIV, AIDS
- medicines for seizures such as phenytoin
- medicines for thyroid problems
- medicines to lower cholesterol such as atorvastatin, cerivastatin, lovastatin, or simvastatin
- methotrexate
- procainamide
- quinidine
- rifampin, rifabutin, or rifapentine
- St. John's Wort
- trazodone
- warfarin
This list may not describe all possible interactions. Give your health care provider a list of all the medicines, herbs, non-prescription drugs, or dietary supplements you use. Also tell them if you smoke, drink alcohol, or use illegal drugs. Some items may interact with your medicine.
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